Maternal regulation of estrogen receptor α methylation

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Maternal regulation of estrogen receptor a methylation

Advances in molecular biology have provided tools for studying the epigenetic factors that modulate gene expression. DNA methylation is an epigenetic modification that can have sustained effects on transcription and is associated with longterm gene silencing. In this review, we focus on the regulation of estrogen receptor alpha (ERa) expression by hormonal and environmental cues, the consequenc...

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ژورنال

عنوان ژورنال: Current Opinion in Pharmacology

سال: 2008

ISSN: 1471-4892

DOI: 10.1016/j.coph.2008.06.018